021-51111890
购物车（）
sales@molnova.cn
Cycloguanil hydrochloride
CAS No. 152-53-4
Cycloguanil hydrochloride ( Chloroguanide Triazine )
产品货号. M20150 CAS No. 152-53-4
Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥413 | 有现货 |
|
| 5MG | ￥624 | 有现货 |
|
| 10MG | ￥1021 | 有现货 |
|
| 25MG | ￥1677 | 有现货 |
|
| 50MG | ￥2989 | 有现货 |
|
| 100MG | ￥4447 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Cycloguanil hydrochloride
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
-
产品描述Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
-
同义词Chloroguanide Triazine
-
通路Microbiology/Virology
-
靶点Parasite
-
受体Parasite
-
研究领域——
-
适应症——
化学信息
-
CAS Number152-53-4
-
分子量288.18
-
分子式C11H14ClN5.ClH
-
纯度>98% (HPLC)
-
溶解度DMSO: 20 mg/mL (69.4 mM);Water: 5 mg/mL (17.35 mM)
-
SMILESCl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Wright JD et al. The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides. Br J Clin Pharmacol. 1995 Apr;39(4):441-4.
产品手册
关联产品
-
8-Deoxygartanin
8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE).
-
Rafoxanide
A salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1.
-
Ganaplacide
Ganaplacide (KAF156, GNF-156)is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains.
